BRINTELLIX PI PDF

BRINTELLIX PI PDF

BRINTELLIX safely and effectively. See full prescribing information for BRINTELLIX. BRINTELLIX (vortioxetine) tablets, for oral use. Initial U.S. Approval: Brintellix is not recommended for the treatment of depression in patients aged less than 18 years since the safety and efficacy of vortioxetine have not been. Product details on treatment with TRINTELLIX (vortioxetine), including available savings if eligible, and support sign-up. Watch videos of actual patients. See full.

Author: Vudotilar Shakatilar
Country: Fiji
Language: English (Spanish)
Genre: Automotive
Published (Last): 22 April 2005
Pages: 250
PDF File Size: 18.45 Mb
ePub File Size: 3.66 Mb
ISBN: 234-7-55161-430-7
Downloads: 84511
Price: Free* [*Free Regsitration Required]
Uploader: Nikolabar

It is recommended that you do not breast-feed while taking Brintellix, as it may be excreted in the milk. By continuing to browse the site you are agreeing to our policy on the use of cookies.

If this occurs, treatment with vortioxetine should be discontinued immediately and symptomatic treatment should be initiated.

Ther Clin Risk Manag. No effect of food on the pharmacokinetics was observed. The information in this monograph is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects.

Lithium, tryptophan No clinically relevant effect was observed during steady-state lithium exposure following co-administration with multiple doses of vortioxetine in healthy subjects. The maximum dose is not recommended to exceed three times the original dose [see Dosage and Administration 2.

You are about to leave this website and enter a website operated by an independent third party. PPHN occurs in one to two per 1, live births in the general population and is associated with substantial neonatal morbidity and mortality. Nausea was the most common adverse reaction reported as a reason for discontinuation. In a patient who requires more urgent treatment of a psychiatric condition, other interventions, including hospitalization, should be considered [see Contraindications ].

  CLOSET WARDROBES DESIGN FILETYPE PDF

Depending on individual patient response, the dose may be increased to a maximum of 20 mg vortioxetine once daily or decreased to a minimum of 5 mg vortioxetine once daily. Brintellix is a registered trade mark of H. Vortioxetine is present in the milk of lactating rats.

Manufacturer and distributor Brintellix is made by Btintellix. Depending on individual patient response, a dose adjustment may be considered see section 4. A prospective longitudinal study was conducted of pregnant women with a history of major depression, who were either on antidepressants or had received antidepressants less than 12 weeks prior to their last menstrual period, and were in remission.

Pack sizes of 14, 28, 56 and 98 film-coated tablets. This risk persists until significant remission occurs.

The tAccess Support Program offers motivational emails packed with positive tips and support for people with depression. Discontinuation brintellx vortioxetine should be considered in patients with symptomatic hyponatraemia and appropriate medical intervention should bringellix instituted. Vortioxetine must not be initiated for at least 14 days after discontinuation of treatment with an irreversible non-selective MAOI. You might ask them to tell you if they think your depression is getting worse, or if they are worried about changes in your behaviour.

The contribution of these activities to vortioxetine’s antidepressant effect has not been established.

The presence or absence of sexual dysfunction among patients entering clinical studies was based on their ASEX scores. Tell your doctor as soon as possible if you notice any of the following: Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk.

  CULTIVO RABANO HIDROPONIA PDF

Vortioxetine

No apparent difference in beintellix plasma protein binding between healthy subjects and subjects with hepatic mild, moderate or renal mild, moderate, severe, ESRD impairment is observed. The mechanism of the antidepressant effect of vortioxetine is not fully understood, but is thought to be related to its enhancement of serotonergic activity in the CNS through inhibition of the reuptake of serotonin 5-HT.

Continue to take Brintellix even if it takes some time before you feel any pu in your condition. Hypersensitivity to the active substance or to any of the excipients listed in section 6. Negligible amounts of unchanged vortioxetine were excreted in the urine up to 48 hours. Haemorrhage Bleeding abnormalities, such bgintellix ecchymoses, purpura and other haemorrhagic events, such as gastrointestinal or gynaecological bleeding, have been reported rarely with the use of antidepressants with serotonergic effect Selective Serotonin Reuptake Inhibitors SSRIs ,Serotonin Norepinephrine Reuptake Inhibitors SNRIs.

TGA eBS – Product and Consumer Medicine Information

Brintellix 15 mg tablets are orange, almond-shaped, biconvex film-coated tablet engraved with “TL” on one side and “15” on the other side. No pharmacodynamic interactions were observed. Marketing authorisation holder 8.

Tell your doctor if you notice any of the following side effects and they worry you: Skin and subcutaneous tissue disorders.

All medicines have risks and benefits.