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Privacy Policy Terms and Conditions. Due to low protein purification efficiency You already recently rated this item. The cycle of de novo thymidylate synthesis is a part of a folate-mediated one-carbon metabolism.

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The increased activity of SHMT in cancer cells indicates that the inhibition of this enzyme, resulting in disturbing of glycine and serine metabolism, can be helpful in cancer therapy. New York ; Chichester: Finding libraries that hold this item Your Web browser is not enabled for JavaScript. Similar Items Related Subjects: In order to select the best conditions of human cSHMT overproduction in bacteria small-scale culture was first performed, and then cells were grown in 4 liters of SB medium.


Write a review Rate this item: Would you also like to submit a review for this item? Find a copy in the library Finding libraries that hold this item The tag allowed the protein binding to the nickel ions.

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Please enter your name. This metabolic pathway includes also purine synthesis and methionine synthesis cycle.

Please enter recipient e-mail address es. Some features powihowactwa WorldCat will not be available. WorldCat is the world’s largest library catalog, helping you find library materials online. The disruption of folate-mediated metabolism, in which the metabolism of serine and glycine plays an important role, is observed in tumor cells. Please enter the message. Your list has reached the maximum number of items. The name field is required. Your request to send this item has been completed.

Affinity chromatography : bioselective adsorption on inert matrices (Book, ) []

Nadprodukcja opwinowactwa bakteriach i oczyszczanie ludzkiej hydroksymetylotransferazy serynowej. Please choose whether or not you want other users to be able to see on your profile that this library is a favorite of yours.

Don’t have an account? Finally, the purified fraction was dialyzed against a suitable buffer and the catalytic activity of the produced protein was determined.

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Advanced Search Find a Library. Cancel Forgot your password? Two SHMT-catalyzed reaction mechanisms have been described. William H Scouten Publisher: William H Scouten Find more information about: The E-mail message field is required. Create lists, bibliographies and reviews: The specific requirements or preferences of your reviewing publisher, classroom teacher, institution or organization should be applied.

Opisano dwa mechanizmy katalizowanej przez SHMT reakcji.

Affinity chromatography : bioselective adsorption on inert matrices

English View all editions and formats Rating: The conversion of serine to glycine is one of three reactions of the thymidylate biosynthesis cycle. Your rating has been recorded. You may have already requested this item. Linked Data More info about Linked Data. Add a review and share your thoughts with other readers. Citations are based on reference standards. Please select Ok if you would like to proceed with this request anyway.

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